NeuroLabWare双光子显微镜

  • 品牌：Neurolabware
  • 货号：Standard/Mesoscope
  • 规格：/
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Neurolabware 由 Adrian Cheng 博士和 Josh Trachtenberg 博士于 2011 年创立。Adrian 拥有数学和物理学学位，之前曾在西雅图艾伦脑科学研究所与 Hongkui Zeng 和 Clay Reid 一起工作。Josh 拥有生理学学位。 他是加州大学洛杉矶分校的神经生物学教授。他曾在加州大学旧金山分校的 Michael Stryker 和冷泉港实验室的 Karel Svoboda 接受培训。 他的实验室使用一系列重要的成像方法来揭示小鼠新皮质中微电路可塑性的机制。

NeuroLabware双光子系统已被超过100+的实验室装机使用并获得高度好评。

部分客户：University of California, Berkeley、Massachusetts Institute of Technology、Sainsbury Wellcome Centre、New York University、Northwestern University、Boston University、McGill University、Yale University、Johns Hopkins University、Duke University、IMEC, Belgium等

以下是Jakob Voigts利用Neurolabware双光子显微镜结合气浮笼行为学的实验，

Somatic and dendritic encoding of spatial variables in retrosplenial cortex differs during 2d navigation
‍J Voigts, MT Harnett, Neuron 105 (2), 237-245. e4

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Garcia-Junco-Clemente, Pablo, Taruna Ikrar, Elaine Tring, Xiangmin Xu, Dario L. Ringach, and Joshua T. Trachtenberg. “An Inhibitory Pull-Push Circuit in Frontal Cortex.” Nature Neuroscience 20, no. 3 (March 2017): 389–92. https://doi.org/10.1038/nn.4483.

Hainmueller, Thomas, and Marlene Bartos. “Parallel Emergence of Stable and Dynamic Memory Engrams in the Hippocampus.” Nature 558, no. 7709 (June 2018): 292. https://doi.org/10.1038/s41586-018-0191-2.

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Heffley, William, Eun Young Song, Ziye Xu, Benjamin Taylor, Mary Anne Hughes, Andrew McKinney, Mati Joshua, and Court Hull. “Coordinated Cerebellar Climbing Fiber Activity Is Gated by Behavioral Context in a Voluntary Motor Regime.” BioRxiv, March 13, 2018, 281055. https://doi.org/10.1101/281055.

Heffley, William, Eun Young Song, Ziye Xu, Benjamin N. Taylor, Mary Anne Hughes, Andrew McKinney, Mati Joshua, and Court Hull. “Coordinated Cerebellar Climbing Fiber Activity Signals Learned Sensorimotor Predictions.” Nature Neuroscience 21, no. 10 (October 2018): 1431. https://doi.org/10.1038/s41593-018-0228-8.

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Jimenez, Luis O., Elaine Tring, Joshua T. Trachtenberg, and Dario L. Ringach. “Local Tuning Biases in Mouse Primary Visual Cortex.” Journal of Neurophysiology 120, no. 1 (April 18, 2018): 274–80. https://doi.org/10.1152/jn.00150.2018.

“Untangling Cortical Maps in Mouse Primary Visual Cortex.” BioRxiv, January 21, 2017, 102079. https://doi.org/10.1101/102079.

Jin, Miaomiao, Jeffrey M. Beck, and Lindsey Glickfeld. “Neuronal Adaptation Reveals a Suboptimal Decoding of Orientation Tuned Populations in the Mouse Visual Cortex.” BioRxiv, October 3, 2018, 433722. https://doi.org/10.1101/433722.

Kandler, Steffen, Dun Mao, Bruce L. McNaughton, and Vincent Bonin. “Encoding of Tactile Context in the Mouse Visual Cortex.” BioRxiv, May 2, 2018, 199364. https://doi.org/10.1101/199364.

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Liang, Liang, Alex Fratzl, Glenn Goldey, Rohan N. Ramesh, Arthur U. Sugden, Josh L. Morgan, Chinfei Chen, and Mark L. Andermann. “A Fine-Scale Functional Logic to Convergence from Retina to Thalamus.” Cell 173, no. 6 (May 31, 2018): 1343-1355.e24. https://doi.org/10.1016/j.cell.2018.04.041.

Livneh, Yoav, Rohan n. Ramesh, christian R. Burgess, Kirsten M. Levandowski, Joseph c. Madara, henning Fenselau, Glenn J. Goldey, et al. “Homeostatic Circuits Selectively Gate Food Cue Responses in Insular Cortex.” Nature 546, no. 7660 (June 29, 2017): 611–16. https://doi.org/10.1038/nature22375.

Madisen, Linda, Aleena R. Garner, Daisuke Shimaoka, Amy S. Chuong, Nathan C. Klapoetke, Lu Li, Alexander van der Bourg, et al. “Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance.” Neuron 85, no. 5 (March 4, 2015): 942–58. https://doi.org/10.1016/j.neuron.2015.02.022.

Mao, Dun, Steffen Kandler, Bruce L. McNaughton, and Vincent Bonin. “Sparse Orthogonal Population Representation of Spatial Context in the Retrosplenial Cortex.” Nature Communications 8 (August 15, 2017). https://doi.org/10.1038/s41467-017-00180-9.

Mineault, Patrick J., Elaine Tring, Joshua T. Trachtenberg, and Dario L. Ringach. “Enhanced Spatial Resolution During Locomotion and Heightened Attention in Mouse Primary Visual Cortex.” The Journal of Neuroscience 36, no. 24 (June 15, 2016): 6382–92. https://doi.org/10.1523/JNEUROSCI.0430-16.2016.

Mols, Katrien, Silke Musa, Bart Nuttin, Liesbet Lagae, and Vincent Bonin. “In Vivo Characterization of the Electrophysiological and Astrocytic Responses to a Silicon Neuroprobe Implanted in the Mouse Neocortex.” Scientific Reports 7 (November 15, 2017). https://doi.org/10.1038/s41598-017-15121-1.

Nelson, Anders, and Richard Mooney. “The Basal Forebrain and Motor Cortex Provide Convergent yet Distinct Movement-Related Inputs to the Auditory Cortex.” Neuron 90, no. 3 (May 4, 2016): 635–48. https://doi.org/10.1016/j.neuron.2016.03.031.

Pluta, Scott R., Evan H. Lyall, Greg I. Telian, Elena Ryapolova-Webb, and Hillel Adesnik. “Surround Integration Organizes a Spatial Map during Active Sensation.” Neuron 94, no. 6 (June 21, 2017): 1220-1233.e5. https://doi.org/10.1016/j.neuron.2017.04.026.

Ramesh, Rohan N., Christian R. Burgess, Arthur U. Sugden, Michael Gyetvan, and Mark L. Andermann. “Intermingled Ensembles in Visual Association Cortex Encode Stimulus Identity or Predicted Outcome.” Neuron, October 11, 2018. https://doi.org/10.1016/j.neuron.2018.09.024.

Ringach, Dario L., Patrick J. Mineault, Elaine Tring, Nicholas D. Olivas, Pablo Garcia-Junco-Clemente, and Joshua T. Trachtenberg. “Spatial Clustering of Tuning in Mouse Primary Visual Cortex.” Nature Communications 7 (August 2, 2016): 12270. https://doi.org/10.1038/ncomms12270.

Salinas, Kirstie J., Dario X. Figueroa Velez, Jack H. Zeitoun, Hyungtae Kim, and Sunil P. Gandhi. “Contralateral Bias of High Spatial Frequency Tuning and Cardinal Direction Selectivity in Mouse Visual Cortex.” The Journal of Neuroscience 37, no. 42 (October 18, 2017): 10125–38. https://doi.org/10.1523/JNEUROSCI.1484-17.2017.

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Socha, Karolina, Matt Whiteway, Daniel Butts, and Vincent Bonin. “Behavioral Response to Visual Motion Impacts Population Coding in the Mouse Visual Thalamus.” BioRxiv, August 1, 2018, 382671. https://doi.org/10.1101/382671.

Tanaka, Masashi, Fangmiao Sun, Yulong Li, and Richard Mooney. “A Mesocortical Dopamine Circuit Enables the Cultural Transmission of Vocal Behaviour.” Nature 563, no. 7729 (November 2018): 117. https://doi.org/10.1038/s41586-018-0636-7.

Tring, Elaine, and Dario Ringach. “On the Subspace Invariance of Population Responses.” BioRxiv, July 4, 2018, 361568. https://doi.org/10.1101/361568.

Voigts, Jakob, and Mark Harnett. “An Animal-Actuated Rotational Head-Fixation System for 2-Photon Imaging during 2-d Navigation.” BioRxiv, March 1, 2018, 262543. https://doi.org/10.1101/262543.

Wekselblatt, Joseph B., Erik D. Flister, Denise M. Piscopo, and Cristopher M. Niell. “Large-Scale Imaging of Cortical Dynamics during Sensory Perception and Behavior.” Journal of Neurophysiology 115, no. 6 (June 1, 2016): 2852–66. https://doi.org/10.1152/jn.01056.2015.